The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Oct. 31, 2013
Applicant:
The Medicines Company (Leipzig) Gmbh, Leipzig, DE;
Inventors:
Peter Herold, Munchenstein, CH;
Mohammed Daghish, Leipzig, DE;
Stjepan Jelakovic, Freiburg, DE;
Friedrich-Alexander Ludwig, Leipzig, DE;
Claudia Reichelt, Leipzig, DE;
Alexander Schulze, Bad Liebenwerda, DE;
Andrea Schweinitz, Jena, DE;
Assignee:
THE MEDICINES COMPANY (LEIPZIG) GMBH, Leipzig, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07K 5/078 (2006.01); C07D 211/34 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07K 5/065 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/06139 (2013.01); C07D 211/34 (2013.01); C07D 401/12 (2013.01); C07D 413/12 (2013.01); C07K 5/06078 (2013.01); A61K 31/445 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.