The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Jul. 28, 2015
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Andrew G. Myers, Boston, MA (US);

Nicholas E. Hill, Arlington, VA (US);

Jakub Svenda, Cambridge, MA (US);

Robert T. Yu, Somerville, MA (US);

Daniel J. Smaltz, Cambridge, MA (US);

Thomas Magauer, Steyr, AT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/04 (2006.01); C07H 15/24 (2006.01); C07H 15/26 (2006.01); C07D 493/22 (2006.01);
U.S. Cl.
CPC ...
C07H 17/04 (2013.01); C07D 493/22 (2013.01); C07H 15/24 (2013.01); C07H 15/26 (2013.01);
Abstract

The present invention relates to trioxacarcin compounds of the formula: or pharmaceutically acceptable forms thereof; wherein R, R, R, R, R, R, R, R, and Rare as defined herein. The present invention also provides processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; and methods of use and treatment.


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