The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
May. 28, 2015
Applicant:
Purdue Pharma L.p., Stamford, CT (US);
Inventors:
Chiyou Ni, Belle Mead, NJ (US);
Bin Shao, Richboro, PA (US);
Laykea Tafesse, Robbinsville, NJ (US);
Jiangchao Yao, Princeton, NJ (US);
Jianming Yu, Plainsboro, NJ (US);
Xiaoming Zhou, Plainsboro, NJ (US);
Assignee:
Purdue Pharma L.P., Stamford, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/81 (2006.01); C07D 213/643 (2006.01); C07D 401/14 (2006.01); C07D 213/30 (2006.01); C07D 401/12 (2006.01); C07D 213/58 (2006.01); C07D 401/04 (2006.01); C07D 213/46 (2006.01); C07D 213/74 (2006.01); C07D 213/79 (2006.01); C07D 213/84 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 213/50 (2006.01); C07D 213/57 (2006.01); C07D 213/65 (2006.01);
U.S. Cl.
CPC ...
C07D 213/81 (2013.01); C07D 213/30 (2013.01); C07D 213/46 (2013.01); C07D 213/50 (2013.01); C07D 213/57 (2013.01); C07D 213/58 (2013.01); C07D 213/643 (2013.01); C07D 213/65 (2013.01); C07D 213/74 (2013.01); C07D 213/79 (2013.01); C07D 213/84 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01);
Abstract
The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R, A, A, E, G, Z, and Zare defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.