The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Apr. 15, 2010
Applicants:
Constance L. Cepko, Newton, MA (US);
Claudio Punzo, Boston, MA (US);
Inventors:
Constance L. Cepko, Newton, MA (US);
Claudio Punzo, Boston, MA (US);
Assignee:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 9/16 (2006.01); C12N 9/88 (2006.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); C12N 9/16 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12Y 301/03011 (2013.01); C12Y 401/01032 (2013.01); C12Y 604/01001 (2013.01); C12N 2799/025 (2013.01); C12N 2830/008 (2013.01); C12N 2840/203 (2013.01);
Abstract
The present invention is directed to methods for the treatment or prevention of starvation in a cell, e.g., a neuronal cell, and methods for the treatment and prevention of disorders associated therewith by the administration of an agent, e.g., a nucleic acid molecule, which enhances the intracellular generation and/or uptake of glucose, pyruvate, lactate, and/or NADPH.