The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Mar. 12, 2014
Applicant:
Seattle Genetics, Inc., Bothell, WA (US);
Inventors:
Hui Li, Clyde Hill, WA (US);
Shan Jiang, Sammamish, WA (US);
Mary Wallace, Bothell, WA (US);
Damon Meyer, Bellevue, WA (US);
Assignee:
Seattle Genetics, Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); A61K 47/48 (2006.01); C07D 519/00 (2006.01); A61K 31/5517 (2006.01); A61K 47/40 (2006.01); B01D 61/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48384 (2013.01); A61K 31/5517 (2013.01); A61K 47/40 (2013.01); B01D 61/145 (2013.01); C07D 519/00 (2013.01); B01D 2315/10 (2013.01); B01D 2315/16 (2013.01);
Abstract
Disclosed are formulations, including both liquid and lyophilized formulations, comprising a benzodiazepine anti-body-drug conjugate (ADC) and a cyclodextrin. Also disclosed are methods of purifying mixtures comprising benzodiazepine anti-body-drug conjugates and process drug-related impurities.