The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Jul. 06, 2015
Applicant:

Technology Innovation Momentum Fund (Israel) Limited Partnership, Tel-Aviv, IL;

Inventors:

Moran Aviv, Rishon-LeZion, IL;

Ludmila Buzhansky, Ariel, IL;

Shmuel Einav, Herzlia, IL;

Zvi Nevo, Herzlia, IL;

Ehud Gazit, Ramat-HaSharon, IL;

Lihi Adler-Abramovich, Herzlia, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61K 47/36 (2006.01); A61L 27/20 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); A61K 8/64 (2006.01); A61K 47/26 (2006.01); C08L 89/00 (2006.01); A61K 8/04 (2006.01); A61K 8/73 (2006.01); A61K 47/18 (2017.01); A61L 27/26 (2006.01); A61Q 19/00 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 47/36 (2013.01); A61K 8/042 (2013.01); A61K 8/64 (2013.01); A61K 8/735 (2013.01); A61K 8/736 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); A61L 27/20 (2013.01); A61L 27/227 (2013.01); A61L 27/26 (2013.01); A61L 27/52 (2013.01); A61Q 19/00 (2013.01); C08L 89/00 (2013.01); A61K 9/1694 (2013.01); A61K 2800/10 (2013.01); A61L 2400/06 (2013.01);
Abstract

Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.


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