The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Sep. 05, 2010
Applicants:

Anna Aronovich, Rehovot, IL;

Dalit Tchorsh-yutsis, Rehovot, IL;

Gideon Rechavi, Tel-Aviv, IL;

Yair Reisner, Old Jaffa, IL;

Inventors:

Anna Aronovich, Rehovot, IL;

Dalit Tchorsh-Yutsis, Rehovot, IL;

Gideon Rechavi, Tel-Aviv, IL;

Yair Reisner, Old Jaffa, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/37 (2006.01); A61K 38/36 (2006.01); A61K 31/4439 (2006.01); A61K 31/727 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/363 (2013.01); A61K 31/4439 (2013.01); A61K 31/727 (2013.01); A61K 38/1816 (2013.01); A61K 38/37 (2013.01);
Abstract

Methods of modulating mobilization of cells from the bone marrow are provided. In a specific embodiment there is provided a method of increasing mobilization of hematopoietic precursors from the bone marrow to the peripheral blood in a subject in need thereof, the method comprising: (a) administering to the subject an agent which downregulates an activity or expression of a coagulation factor or an effector thereof; and (b) harvesting the hematopoietic precursors from the peripheral blood.


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