The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Sep. 27, 2010
Solomon S. Steiner, Mount Kisco, NY (US);
Robert Hauser, Columbia, MD (US);
Ming LI, Yorktown Heights, NY (US);
Robert Feldstein, Yonkers, NY (US);
Roderike Pohl, Sherman, CT (US);
Solomon S. Steiner, Mount Kisco, NY (US);
Robert Hauser, Columbia, MD (US);
Ming Li, Yorktown Heights, NY (US);
Robert Feldstein, Yonkers, NY (US);
Roderike Pohl, Sherman, CT (US);
Albireo Pharma, Inc., Boston, MA (US);
Abstract
A formulation composed of a sugar such as glucose and a surfactant such as myristoyl lysophosphocholine (LMPC) has been designed to stabilize both hydrophilic and hydrophobic portions of the glucagon molecule, under prolonged physiological conditions, in a formulation that is sufficiently similar to the pH and osmolarity of plasma so as not to induce or to minimize site irritation. The combination of a simple sugar and an surfactant stabilizes the glucagon molecule in an aqueous solution for seven days at 37° C.