The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Mar. 07, 2011
Applicants:

David J. Mooney, Sudbury, MA (US);

Cristina Borselli, Naples, IT;

Herman Vandenburgh, Providence, RI (US);

Dimitry Shvartsman, Belmont, MA (US);

Hannah Storrie, Chapel Hill, NC (US);

Jeff Lichtman, Cambridge, MA (US);

Inventors:

David J. Mooney, Sudbury, MA (US);

Cristina Borselli, Naples, IT;

Herman Vandenburgh, Providence, RI (US);

Dimitry Shvartsman, Belmont, MA (US);

Hannah Storrie, Chapel Hill, NC (US);

Jeff Lichtman, Cambridge, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 5/00 (2006.01); A61K 38/18 (2006.01); A61K 38/30 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61K 35/34 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 38/1866 (2013.01); A61K 35/12 (2013.01); A61K 35/34 (2013.01); A61K 38/18 (2013.01); A61K 38/30 (2013.01); A61L 27/3612 (2013.01); A61L 27/3826 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 2300/414 (2013.01); A61L 2400/06 (2013.01); A61L 2400/16 (2013.01); C08L 2201/12 (2013.01);
Abstract

An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time.


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