The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Nov. 19, 2012
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning, CN;
University of California, Irvine, Irvine, CA (US);
Xinmiao Liang, Liaoning, CN;
Chaoran Wang, Liaoning, CN;
Xiuli Zhang, Liaoning, CN;
Yan Zhang, Irvine, CA (US);
Zhiwei Wang, Irvine, CA (US);
Olivier Civelli, Irvine, CA (US);
Yanxiong Ke, Liaoning, CN;
Lien Wang, Irvine, CA (US);
DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES, Dalian, CN;
UNIVERSITY OF CALIFORNIA, IRVINE, Irvine, CA (US);
Abstract
A method of treating nervous system diseases associated with dopamine receptors comprising administering a patent in need a compound having a structure of general formula (I) or a pharmaceutical acceptable salt, hydrate, or solvate thereof in a pharmaceutically effective amount, and a method of making the compound having the structure of general formula (I) or a pharmaceutical acceptable salt, hydrate, or solvate thereof. The compound of formula (I) has multiple pharmacological functions such as the functions of activating opioid receptors and blocking dopamine D2 receptors, and has good physicochemical properties and oral bioavailability. General animal experiments show that such a compound has significant and long-lasting analgesic and calming effects and can be used to treat pain and other mental illnesses.