The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2017
Filed:
Nov. 22, 2011
Applicants:
Krishna Menon, North Reading, MA (US);
Wayne O. Aruda, Boca Raton, FL (US);
Inventors:
Krishna Menon, North Reading, MA (US);
Wayne O. Aruda, Boca Raton, FL (US);
Assignee:
Cellceutix Corporation, Beverly, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/44 (2006.01); A61K 31/275 (2006.01); C07C 255/46 (2006.01); C07C 255/45 (2006.01); C07C 255/00 (2006.01); A61K 31/277 (2006.01); A61K 31/4375 (2006.01); A61K 31/472 (2006.01); A61K 31/513 (2006.01); C07C 335/32 (2006.01); C07D 213/57 (2006.01); C07D 215/12 (2006.01); C07D 217/02 (2006.01); C07D 217/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/275 (2013.01); A61K 31/277 (2013.01); A61K 31/4375 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/472 (2013.01); A61K 31/513 (2013.01); C07C 335/32 (2013.01); C07D 213/57 (2013.01); C07D 215/12 (2013.01); C07D 217/02 (2013.01); C07D 217/14 (2013.01); C07D 471/04 (2013.01);
Abstract
Disclosed are nitrile derivatives and pharmaceutical compositions comprising nitrile derivatives. The pharmaceutical compositions comprise compounds of the formula I and the pharmaceutically acceptable salts of such compounds. Also disclosed are processes for the preparation of such compounds, intermediates used in the preparation of such compounds, and the uses of such compounds in treating hyperproliferative diseases, inflammatory diseases and viral and bacterial infections and inducing apoptosis in cancer cells.