The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2017

Filed:

Jul. 06, 2011
Applicants:

David E. Anderson, Boston, MA (US);

Andrei Ogrel, Russell, CA;

Ronald Erwin Boch, Ottawa, CA;

Jeff Baxter, Philadelphia, PA (US);

Inventors:

David E. Anderson, Boston, MA (US);

Andrei Ogrel, Russell, CA;

Ronald Erwin Boch, Ottawa, CA;

Jeff Baxter, Philadelphia, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 39/145 (2006.01); A61K 47/06 (2006.01); A61K 9/00 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 47/06 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01);
Abstract

The present disclosure provides compositions and methods useful for treating influenza. As described herein, provided compositions and methods are based on the development of certain compositions that include an influenza virus hemagglutinin antigen in combination with lipid vesicles that include a non-ionic surfactant (NISVs) and optionally an adjuvant. In certain embodiments, provided compositions remain potent even when they are not stored in a standard cold-chain system (i.e., they are thermostable).


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