The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Apr. 02, 2015
Applicant:

Stc.unm, Albuquerque, NM (US);

Inventors:

Ke Jian Liu, Albuquerque, NM (US);

Wenlan Liu, Albuquerque, NM (US);

Graham Timmins, Albuquerque, NM (US);

Rong Pan, Albuquerque, NM (US);

Assignee:

STC.UNM, Albuquerque, NM (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 2333/4703 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/52 (2013.01);
Abstract

Methods and apparatus for determining blood brain barrier (BBB) damage and treating patients who may have suffered from BBB damage due to an ischemic event are provided. The methods and apparatus involve detecting the presence of cleaved occludin fragments in a sample of blood. According to some embodiments, the method further provides determining the degree of BBB damage based on the concentration of occludin fragments in the sample. In further embodiments the present disclosure provides kits for detecting the presence of occludin fragments in a blood sample.


Find Patent Forward Citations

Liu, Ke. (2017). Blood biomarker for early blood brain barrier disruption in ischemic stroke (U.S. Patent No. 9606129). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9606129

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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