The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Jul. 16, 2015
Applicants:
City of Hope, Duarte, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
John Rossi, Alta Loma, CA (US);
Jiehua Zhou, Monrovia, CA (US);
Marc Weinberg, Encinitas, CA (US);
Kevin Morris, Sierra Madre, CA (US);
Assignees:
CITY OF HOPE, Duarte, CA (US);
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 48/00 (2006.01); C07H 21/04 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12N 2310/16 (2013.01);
Abstract
Provided herein are fluoropyrimidine-modified RNA aptamers capable of binding CCR5. The compositions and methods provided herein are, inter alia, useful for the delivery of anti-viral drugs (e.g., siRNAs) and preventing HIV entry into a target cell.