The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Mar. 14, 2014
Applicant:

Ibis Biosciences, Inc., Carlsbad, CA (US);

Inventors:

David J. Ecker, Encinitas, CA (US);

Todd P. Michael, Carlsbad, CA (US);

Lendell L. Cummins, San Diego, CA (US);

Mark W. Eshoo, San Diego, CA (US);

Stanley T. Motley, Carlsbad, CA (US);

Danny M. Chou, Carlsbad, CA (US);

Assignee:

IBIS BIOSCIENCES, INC., Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12Q 1/6883 (2013.01); C12N 2310/10 (2013.01); C12N 2320/11 (2013.01); C12Q 2600/154 (2013.01);
Abstract

Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. Further provided herein are systems and methods for the identification of target sites for regulation by piRNAs.


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