The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Apr. 18, 2011
Applicants:

Simon Barry, Longwood, AU;

Doreen Krumbiegel, Edwardstown, AU;

Nicola Ga-ling Eastaff-leung, Blackwood, AU;

Ian Cameron Nicholson, Highbury, AU;

Heddy Zola, Evandale, AU;

Inventors:

Simon Barry, Longwood, AU;

Doreen Krumbiegel, Edwardstown, AU;

Nicola Ga-Ling Eastaff-Leung, Blackwood, AU;

Ian Cameron Nicholson, Highbury, AU;

Heddy Zola, Evandale, AU;

Assignee:

MEDVET SCIENCE PTY LTD., Underdale, South Australia, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/38 (2006.01); G01N 33/569 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/38 (2013.01); C07K 16/28 (2013.01); C12N 5/0637 (2013.01); G01N 33/56972 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure provides an isolated protein comprising at least one antibody variable region that is capable of binding to peptidase inhibitor 16 (PI16), wherein the protein is also capable of competitively inhibiting binding of an antibody produced by a hybridoma designated CRCBT-02-001 deposited with the ATCC under Accession Number PTA-10685 to PI16. The present invention also provides use of the protein, e.g., in diagnosis, therapy or to isolate cells, preferably Treg cells.


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