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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9605056 B1

PDFFull Text
Expired
Date of Patent:
Mar. 28, 2017

Filed:

Oct. 08, 2013

Antibodies recognizing alpha-synuclein

Applicant:

Prothena Biosciences Limited, Dublin, IE;

Inventors:

Robin Barbour, Walnut Creek, CA (US);

Kate Dora Games Thiel, Belmont, CA (US);

Tarlochan S. Nijjar, Orinda, CA (US);

Assignee:

PROTHENA BIOSCIENCES LIMITED, , IE;

Attorney:

Alston & Bird LLP

Primary Examiner:

Adam M Weidner

Assistant Examiner:

Aurora M Fontainhas

Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/00 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 49/0004 (2013.01); A61K 2039/505 (2013.01); A61K 2039/6056 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/92 (2013.01); G01N 33/6896 (2013.01);
Abstract

The invention provides monoclonal antibody 5C1 and related antibodies. The 5C1 antibody binds to an epitope within residues 118-126 of α-synuclein. The antibodies of the invention are useful, for example, for treating and/or diagnosing disorders associated with α-synuclein, particularly accumulation of α-synuclein deposits. Such disorders include Lewy body diseases, such as Parkinson's disease, Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy (MSA).

Find Patent Forward Citations

Barbour, Robin. (2017). Antibodies recognizing alpha-synuclein (U.S. Patent No. 9605056). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9605056

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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