The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Dec. 11, 2015
Applicant:
Reform Biologics, Llc, Cambridge, MA (US);
Inventors:
David S. Soane, Chestnut Hill, MA (US);
Philip Wuthrich, Belmont, MA (US);
Rosa Casado Portilla, Peabody, MA (US);
Robert P. Mahoney, Newbury, MA (US);
Mark Moody, Concord, MA (US);
Assignee:
REFORM BIOLOGICS, LLC, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); A61K 38/38 (2006.01); A61K 38/47 (2006.01); A61K 47/18 (2017.01); A61K 47/22 (2006.01); A61K 47/42 (2017.01); A61K 47/48 (2006.01); C12N 9/36 (2006.01); C12N 9/96 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); A61K 38/385 (2013.01); A61K 38/47 (2013.01); A61K 47/18 (2013.01); A61K 47/183 (2013.01); A61K 47/22 (2013.01); A61K 47/42 (2013.01); A61K 47/48215 (2013.01); C12N 9/2462 (2013.01); C12N 9/96 (2013.01); A61K 39/39591 (2013.01); C12Y 302/01017 (2013.01);
Abstract
The invention encompasses formulations and methods for the production thereof that permit the delivery of concentrated protein solutions. The inventive methods can yield a lower viscosity liquid formulation or a higher concentration of therapeutic or nontherapeutic proteins in the liquid formulation, as compared to traditional protein solutions.