The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Feb. 24, 2012
Applicants:

María Eloísa Yuste Herranz, Barcelona, ES;

Víctor Sánchez Merino, Barcelona, ES;

Carolina Ferreira, Barcelona, ES;

Inventors:

María Eloísa Yuste Herranz, Barcelona, ES;

Víctor Sánchez Merino, Barcelona, ES;

Carolina Ferreira, Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/16 (2006.01); G01N 33/68 (2006.01); C07K 14/005 (2006.01); C12N 15/10 (2006.01); C07K 16/10 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C07K 16/1063 (2013.01); C12N 15/1037 (2013.01); G01N 33/56988 (2013.01); G01N 33/6854 (2013.01); A61K 39/00 (2013.01); C07K 2317/76 (2013.01); C12N 2740/16043 (2013.01); C12N 2740/16122 (2013.01); C12N 2799/027 (2013.01); G01N 2333/162 (2013.01); G01N 2469/20 (2013.01);
Abstract

The invention relates to a method for rapid immunogen selection (RIS) based on the binding a library of recombinant viruses containing randomized HIV gp120 variants of a surface polypeptide displayed to said neutralizing antibodies. The invention relates as well to the use of the HIV gp120 immunogens isolated according to the RIS method of the invention in medicine for the treatment of diseases caused by a virus and in diagnosis for the identification of neutralizing antibodies in a patient.


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