The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Aug. 31, 2012
Eung-soo Kim, Seoul, KR;
Kyu Boem Han, Daejeon, KR;
Shuangjun Lin, Shanghai, CN;
Dekun Kong, Shanghai, CN;
Linquan Bai, Shanghai, CN;
Zixin Deng, Shanghai, CN;
David H. Sherman, Ann Arbor, MI (US);
Mi-jin Lee, Incheon, KR;
Eung-Soo Kim, Seoul, KR;
Kyu Boem Han, Daejeon, KR;
Shuangjun Lin, Shanghai, CN;
Dekun Kong, Shanghai, CN;
Linquan Bai, Shanghai, CN;
Zixin Deng, Shanghai, CN;
David H. Sherman, Ann Arbor, MI (US);
Mi-Jin Lee, Incheon, KR;
INHA-INDUSTRY PARTNERSHIP INSTITUTE, Incheon, KR;
Abstract
The present invention relates to a novel polyene compound similar to nystatin, a method for preparing the same, and an antifungal drug comprising the novel polyene compound as an active ingredient. Compared to nystatin comprising one sugar, NNP, which is the polyene compound similar to nystatin, displays 300 times higher solubility and ten times lower cytotoxicity while maintaining antifungal activity, and thus can be useful in developing a novel polyene antifungal agent having improved solubility and less toxicity in terms of pharmacokinetics.