The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Oct. 31, 2013
Nerviano Medical Sciences S.r.l, Nerviano (MI), IT;
Maria Menichincheri, Milan, IT;
Mauro Angiolini, Gavirate, IT;
Jay Aaron Bertrand, Didcot, GB;
Michele Caruso, Milan, IT;
Paolo Polucci, Cassina Rizzardi, IT;
Francesca Quartieri, Arona, IT;
Barbara Salom, Vedano al Lambro, IT;
Matteo Salsa, Bellinzago Novarese, IT;
Fabio Zuccotto, Milan, IT;
NERVIANO MEDICAL SCIENCES S.R.L., Nerviano (MI), IT;
Abstract
The present invention relates to substituted pyrimidinyl- and pyridinylpyrrolopyridinone compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions containing these compounds.