The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Jan. 22, 2016
Applicants:

University of Mysore, Mysore, IN;

National University of Singapore, Singapore, SG;

Bangalore University, Bengaluru, IN;

Cambridge Enterprise Ltd, Cambridge, GB;

Inventors:

Kanchugarakoppal Subbegowda Rangappa, Mysore, IN;

Basappa, Bangalore, IN;

Chakrabhavi Dhananjaya Mohan, Mysore, IN;

Shobith Rangappa, Sapporo, JP;

Hanumantharayappa Bharathkumar, Bangalore, IN;

Gautam Sethi, Singapore, SG;

Andreas Bender, Cambridge, GB;

Peter Edward Lobie, Singapore, SG;

Kam Man Hui, Singapore, SG;

Alan Prem Kumar, Singapore, SG;

Vijay Kumar Pandey, Singapore, SG;

Julian Fuchs, Cambridge, GB;

Muthu Kumaraswamy Shanmugam, Singapore, SG;

Krishna Bulusu, Cambridge, GB;

Xiaoyun Dai, Singapore, SG;

Feng Li, Singapore, SG;

Amudha Deivasigamani, Singapore, SG;

Assignees:

UNIVERSITY OF MYSORE, Karnataka, IN;

NATIONAL UNIVERSITY OF SINGPORE, Singapore, SG;

BANGALORE UNIVERSITY, Karnataka, IN;

CAMBRIDGE ENTERPRISE LTD, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 265/16 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 265/16 (2013.01);
Abstract

The present disclosure relates to compound of structural Formula I and a method for preparing said compounds. The disclosure further relates to a method of employing the Formula I compounds for modulation of Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway in cancer cells, and the corresponding use of compound of Formula I as anti-cancer agents.


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