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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9604965 B1

PDFFull Text
Date of Patent:
Mar. 28, 2017

Filed:

Jan. 12, 2015

Substituted pyridazines as skeletal muscle modulators

Applicant:

Cytokinetics, Inc., South San Francisco, CA (US);

Inventors:

Luke W. Ashcraft, San Francisco, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Scott Collibee, San Carlos, CA (US);

Chihyuan Chuang, Millbrae, CA (US);

Jeff Gardina, South San Francisco, CA (US);

Bradley P. Morgan, Moraga, CA (US);

Alex R. Muci, San Francisco, CA (US);

Xiangping Qian, Foster City, CA (US);

Jeffrey Warrington, San Mateo, CA (US);

Zhe Yang, Daly City, CA (US);

Pu-Ping Lu, Foster City, CA (US);

Antonio Romero, San Mateo, CA (US);

Assignee:

Cytokinetics, Inc., South San Francisco, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/50 (2006.01); C07D 237/20 (2006.01); C07D 401/12 (2006.01); C07D 237/24 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 409/14 (2006.01); C07D 411/04 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); C07D 513/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/50 (2013.01); C07D 237/20 (2013.01); C07D 237/24 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 411/04 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 513/04 (2013.01);
Abstract

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, X and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

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