The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Mar. 04, 2015
Applicant:

Owl Biomedical, Inc., Goleta, CA (US);

Inventors:

John S Foster, Santa Barbara, CA (US);

Nicholas C. Martinez, Santa Barbara, CA (US);

Daryl W. Grummitt, Santa Barbara, CA (US);

Ralf-Peter Peters, Bergisch Gladbach, DE;

Christian Peth, Düsseldorf, DE;

Markus Nagel, Frechen, DE;

Assignee:

Owl biomedical, Inc., Goleta, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); F16K 99/00 (2006.01); B81B 7/00 (2006.01); G01N 15/14 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502738 (2013.01); B81B 7/00 (2013.01); F16K 99/0046 (2013.01); G01N 15/1484 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/12 (2013.01); B01L 2400/0622 (2013.01); B01L 2400/0633 (2013.01); B01L 2400/0644 (2013.01); G01N 15/1459 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01);
Abstract

A MEMS-based cell sorter is disclosed, which uses a novel combination of features to accomplish the cell sorting using a microfabricated cell sorting valve housed in a disposable cartridge. The features include an interposer that provides fluid communication between the microfluidic passages in the silicon substrate and a plurality of fluid reservoirs in the cartridge, including a sample, sort and waste reservoir The disposable cartridge may include other features that assist in the handling of small volumes of fluids, such as a siphon region in the sort reservoir and funnel-shaped regions in the sample and waste reservoirs. A mixing mechanism may be provided for stirring the contents of the sample reservoir.


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