The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Dec. 29, 2015
Applicants:
Positec Power Tools (Suzhou) CO Ltd, Jiangsu Province, CN;
Pu Chen, Waterloo, CA;
Inventors:
Pu Chen, Waterloo, CA;
Mousa Jafari, Waterloo, CA;
Wen Xu, Waterloo, CA;
Baoling Chen, Waterloo, CA;
Ran Pan, Waterloo, CA;
Nedra Karunaratne, Kandy, LK;
Assignees:
Positec Power Tools (Suzhou) Co LTD, Jiangsu Province, CN;
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 47/48 (2006.01); A61K 31/713 (2006.01); C12N 15/87 (2006.01); C07K 14/47 (2006.01); C12N 15/11 (2006.01); C07K 19/00 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48323 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/713 (2013.01); C07K 14/4723 (2013.01); C07K 19/00 (2013.01); C12N 15/111 (2013.01); C12N 15/1135 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2320/51 (2013.01);
Abstract
Peptides that have been found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets are disclosed. Complexes that include one of the peptides and a cargo molecule are disclosed, wherein the peptide and the cargo molecule are coupled non-covalently. Also disclosed are methods of producing and using the peptides/complexes.