The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Dec. 04, 2015
Applicant:
Mahendra R. Patel, Milltown, NJ (US);
Inventor:
Mahendra R. Patel, Milltown, NJ (US);
Assignee:
Navinta, LLC, Ewing, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); A61K 47/20 (2006.01); A61K 31/4184 (2006.01); A61K 9/08 (2006.01); A61K 47/18 (2017.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 47/20 (2013.01); A61K 9/08 (2013.01); A61K 31/4184 (2013.01); A61K 47/10 (2013.01); A61K 47/18 (2013.01);
Abstract
The present invention provides stable bendamustine-containing pharmaceutical compositions suitable for long term storage. The compositions include bendamustine, a pharmaceutically acceptable salt, and/or a hydrate form thereof, a solvent mixture of N,N-dimethylacetamide and glycerin, and an antioxidant. The bendamustine-containing compositions have less than about 2% of total impurities after two month storage at 25° C./60% RH. The pharmaceutical compositions may be used for treating neoplastic diseases.