The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Feb. 20, 2014
Applicant:
University of Miami, Miami, FL (US);
Inventors:
Eckhard R. Podack, Coconut Grove, FL (US);
Taylor H. Schreiber, Miami, FL (US);
Samia Q. Khan, Miami, FL (US);
Assignee:
University of Miami, Miami, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 14/52 (2006.01); C07K 14/525 (2006.01); A61K 31/436 (2006.01); A61K 38/20 (2006.01); C07K 14/55 (2006.01); A61K 47/48 (2006.01); A61K 31/7088 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/436 (2013.01); A61K 31/7088 (2013.01); A61K 38/20 (2013.01); A61K 38/2013 (2013.01); A61K 39/395 (2013.01); A61K 47/48415 (2013.01); C07K 14/55 (2013.01); C07K 14/52 (2013.01); C07K 16/246 (2013.01); C07K 2319/30 (2013.01);
Abstract
Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific immune responses, are described. Also described are combination therapies that include the administration of a TNFRSF25 agonist and an interleukin (e.g., IL-2) and/or an mTOR inhibitor (e.g., rapamycin).