The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Nov. 09, 2015
Applicant:
Isis Innovation Limited, Oxford, GB;
Inventors:
Alexander Douglas, Oxford, GB;
Simon Draper, Oxford, GB;
Adrian Hill, Oxford, GB;
Andrew Williams, Oxford, GB;
Joseph Illingworth, Matlock, GB;
Assignee:
Oxford University Innovation Limited, Oxford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); C07K 16/20 (2006.01); A61K 39/39 (2006.01); C07K 14/445 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); C12N 15/115 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61K 39/39 (2013.01); C07K 14/445 (2013.01); C07K 16/205 (2013.01); C12N 7/00 (2013.01); C12N 15/115 (2013.01); C12N 15/86 (2013.01); A61K 2039/507 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); C07K 2317/76 (2013.01); C12N 2310/16 (2013.01); C12N 2710/10341 (2013.01); C12N 2710/10371 (2013.01); C12N 2710/24141 (2013.01); C12N 2710/24171 (2013.01);
Abstract
There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising a Reticulocyte-binding protein Homologue 5 (PfRH5) antigen having at least 90% identity with SEQ ID NO: 1, or a fragment thereof; or which comprise a viral vector that expresses PfRH5 antigen having at least 90% identity with SEQ ID NO: 2, or a fragment thereof.