The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
Mar. 12, 2013
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Kosuke Tsukamoto, Osaka, JP;
Monty Krieger, Needham, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/775 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 45/06 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2710/10032 (2013.01); C12N 2710/10041 (2013.01); C12N 2740/15032 (2013.01); C12N 2740/15041 (2013.01);
Abstract
The invention provides methods for treating tissue damage associated with impaired blood flow using ApoD, or an active variant thereof, or an agent that increases the expression of ApoD. The invention also encompasses active variants of ApoD for use in the methods.