The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Dec. 03, 2013
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Michael A. Caligiuri, Columbus, OH (US);

Jianhua Yu, Columbus, OH (US);

Shun He, Columbus, OH (US);

Rossana Trott, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 35/17 (2015.01); A61K 31/7105 (2006.01); A61K 45/06 (2006.01); A61K 9/127 (2006.01); A61K 38/20 (2006.01); A01K 67/027 (2006.01); A61K 38/21 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A01K 67/0275 (2013.01); A61K 9/127 (2013.01); A61K 31/7105 (2013.01); A61K 38/20 (2013.01); A61K 38/208 (2013.01); A61K 38/2013 (2013.01); A61K 38/2086 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); A01K 2217/052 (2013.01); A01K 2217/075 (2013.01); A01K 2217/15 (2013.01); A01K 2227/00 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A01K 2267/0337 (2013.01); A61K 9/5161 (2013.01);
Abstract

Methods and compositions involving miR-122, miR-15, miR-21, and miR-155, which are useful for the treatment of various diseases, such as cancers, are described. Further described are methods and compositions useful for increasing, activating, or regulating NK cells and surface antigens.


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