The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Nov. 08, 2013
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Edouard S. Bouvier, Stow, MA (US);

Bruce J. Compton, Lexington, MA (US);

John C. Gebler, Hopkinton, MA (US);

Martin Gilar, Franklin, MA (US);

Ying Q. Yu, Uxbridge, MA (US);

Peter J. Lee, Westborough, MA (US);

Elizabeth K. Kane, Sutton, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08L 89/00 (2006.01); C12N 9/76 (2006.01); C12Q 1/37 (2006.01); C12P 21/06 (2006.01); G01N 27/447 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); C12P 21/06 (2013.01); G01N 27/44726 (2013.01); G01N 27/44747 (2013.01); G01N 33/5306 (2013.01);
Abstract

The present invention provides methods for enhancing chemical reactions of molecules, e.g., biomolecules, with destructible surfactants. The chemical reactions may involve and/or be associate with analysis, e.g., solubilizing, separating, purifying and/or characterizing the molecules. In one aspect, the anionic surfactants of the present invention may be selectively broken up at relatively low pH. The resulting breakdown products of the surfactants may be removed from the molecule/sample with relative ease. The invention has applicability in a variety of analytical techniques.


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