The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Feb. 28, 2013
Applicants:

Peter Jan Leonard Mario Quaedflieg, Geleen, NL;

Timo Nuijens, Geleen, NL;

Inventors:
Assignee:

ENZYPEP B.V., Geleen, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12P 21/00 (2006.01); C07K 1/02 (2006.01); C07K 1/04 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C07K 1/02 (2013.01); C07K 1/026 (2013.01); C07K 1/04 (2013.01); C07K 1/042 (2013.01);
Abstract

Method for enzymatically synthesizing an oligopeptide, comprising the coupling of an (optionally N-protected) protected oligopeptide ester with an (optionally C-protected) protected oligopeptide nucleophile in an organic solvent or an organic solvent mixture having a water content of 0.1 vol % or less, by a subtilisin in any possible form.


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