The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Mar. 22, 2013
Applicants:

Michael Crowe, Redwood City, CA (US);

Michael Foulkes, Redwood City, CA (US);

Giancarlo Francese, Basel, CH;

Dominique Grimler, Basel, CH;

Ernst Kuesters, Basel, CH;

Kurt Laumen, Basel, CH;

Yunzhong LI, Changshu, CN;

Changxue Lin, Changshu, CN;

Jovana Nazor, Redwood City, CA (US);

Thomas Ruch, Basel, CH;

Derek Smith, Redwood City, CA (US);

Shiwei Song, Redwood City, CA (US);

Shangjun Teng, Changshu, CN;

Inventors:

Michael Crowe, Redwood City, CA (US);

Michael Foulkes, Redwood City, CA (US);

Giancarlo Francese, Basel, CH;

Dominique Grimler, Basel, CH;

Ernst Kuesters, Basel, CH;

Kurt Laumen, Basel, CH;

Yunzhong Li, Changshu, CN;

Changxue Lin, Changshu, CN;

Jovana Nazor, Redwood City, CA (US);

Thomas Ruch, Basel, CH;

Derek Smith, Redwood City, CA (US);

Shiwei Song, Redwood City, CA (US);

Shangjun Teng, Changshu, CN;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/12 (2006.01); C07D 209/16 (2006.01); C12P 17/10 (2006.01); C07D 405/06 (2006.01); C07D 471/20 (2006.01); C07D 209/14 (2006.01); C07D 209/34 (2006.01); C12N 9/10 (2006.01); C07D 209/38 (2006.01);
U.S. Cl.
CPC ...
C12P 17/10 (2013.01); C07D 209/12 (2013.01); C07D 209/14 (2013.01); C07D 209/34 (2013.01); C07D 209/38 (2013.01); C07D 405/06 (2013.01); C07D 471/20 (2013.01); C12N 9/1096 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present invention relates to processes and intermediates useful for the manufacture of spiroindolone compounds such as (1'R,3′S)-5,7′-dichloro-6′-fluoro-3′-methyl-2′,3′,4′,9′-tetrahydrospiro[indoline-3,1′-pyrido[3,4-b]indol]-2-one and salts and hydrates and solvates thereof.


Find Patent Forward Citations

Loading…