The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Jan. 04, 2016
Applicant:

Aveo Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Sylvie Vincent, Somerville, MA (US);

William M. Winston, Jr., Marlborough, MA (US);

Fang Wang, Melrose, MA (US);

Solly Weiler, Newton, MA (US);

Kristan Meetze, Lexington, MA (US);

Lyne Breault, Roslindale, MA (US);

Steve Bottega, Cambridge, MA (US);

Ting Chen, Acton, MA (US);

Michael DePrima, Somerville, MA (US);

Christina Fleet, Melrose, MA (US);

Steven Tyler, Boston, MA (US);

Jin-Kyeung Woo, Newton, MA (US);

Jeno Gyuris, Lincoln, MA (US);

Assignee:

AVEO Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/32 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); C07K 16/30 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.


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