The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Mar. 29, 2016
Applicant:

Pomona Ricerca S.r.l., Turin, IT;

Inventors:

Roberto Burioni, Rimini, IT;

Massimo Clementi, Milan, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C07K 16/10 (2006.01); A61K 47/48 (2006.01); C07K 16/42 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1018 (2013.01); A61K 47/4853 (2013.01); C07K 16/4216 (2013.01); C12N 15/74 (2013.01); G01N 33/686 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); G01N 2469/00 (2013.01);
Abstract

Monoclonal antibodies directed against the influenza A virus are described, which have the advantageous and unpredicted property of being able to bind a plurality of subtypes of the influenza A virus. One preferred embodiment is the antibody designated as Fab28, which displays a neutralizing activity against a plurality of subtypes of the influenza A virus. Anti-idiotype antibodies directed against the monoclonal antibodies described herein, immunogenic or vaccine compositions comprising the monoclonal antibodies of the invention are also described, as well as therapeutic, prophylactic and diagnostic applications for the monoclonal antibodies described herein. The monoclonal antibodies can also be used for testing antibody preparations to be used as vaccines.


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