The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Mar. 14, 2014
Applicant:
Epizyme, Inc., Cambridge, MA (US);
Inventors:
Richard Chesworth, Concord, MA (US);
Lorna Helen Mitchell, Cambridge, MA (US);
Gideon Shapiro, Gainesville, FL (US);
Kerren Kalai Swinger, Lexington, MA (US);
Assignee:
Epizyme, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); A61K 31/415 (2006.01); A61K 31/4155 (2006.01); C07D 401/04 (2006.01); C07D 403/08 (2006.01); C07D 405/04 (2006.01); C07D 405/08 (2006.01); C07D 405/12 (2006.01); C07D 493/10 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 231/12 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 403/08 (2013.01); C07D 405/04 (2013.01); C07D 405/08 (2013.01); C07D 405/12 (2013.01); C07D 493/10 (2013.01);
Abstract
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.