The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Oct. 15, 2015
Applicants:

Seoul National University R&db Foundation, Seoul, KR;

Postech Academy-industry Foundation, Pohang-si, KR;

Inventors:

Sung Key Jang, Pohang-si, KR;

Byeong Moon Kim, Seoul, KR;

Il Hak Bae, Daegu, KR;

Jin Kyu Choi, Pohang-si, KR;

Sun Ju Keum, Seongnam-si, KR;

Seung Gi Lee, Changwon-si, KR;

Hee Sun Kim, Naju-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/16 (2006.01); C07D 207/24 (2006.01); C07D 277/06 (2006.01); C07D 211/60 (2006.01); C07K 5/062 (2006.01); C07K 5/065 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); A23L 33/10 (2016.08); C07D 207/24 (2013.01); C07D 211/60 (2013.01); C07D 277/06 (2013.01); C07D 405/14 (2013.01); C07K 5/06026 (2013.01); C07K 5/06034 (2013.01); C07K 5/06078 (2013.01); A23V 2002/00 (2013.01);
Abstract

The disclosed compounds have antiviral activity against C-type virus, an optical isomer thereof, a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating liver disease caused by hepatitis C virus. The benzidine derivative according to the present invention has excellent antiviral activity against hepatitis C virus and exhibits excellent medicinal activity in the living body, and thus the pharmaceutical composition containing the same as an active ingredient can be useful as a pharmaceutical composition for preventing or treating liver disease, such as acute hepatitis C, chronic hepatitis C, cirrhosis, or hepatocellular carcinoma, caused by C-type virus.


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