The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Oct. 23, 2014
Applicant:
Phanos Technologies, Inc., Los Angeles, CA (US);
Inventor:
Brian D. Gray, Wayne, PA (US);
Assignee:
PHANOS TECHNOLOGIES, INC., Los Angeles, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61B 10/00 (2006.01); A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61K 49/00 (2006.01); C09B 23/01 (2006.01); C09B 23/04 (2006.01); C09B 23/06 (2006.01); C09B 23/08 (2006.01); G01N 33/58 (2006.01); C09B 55/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0032 (2013.01); C09B 23/0066 (2013.01); C09B 23/04 (2013.01); C09B 23/06 (2013.01); C09B 23/083 (2013.01); C09B 23/086 (2013.01); C09B 55/009 (2013.01); G01N 33/582 (2013.01);
Abstract
The invention relates to a family of dyes which fluoresce in the UV-VIS, far red and near infrared wavelengths of the spectrum and possess asymmetric lipophilic alkyl chains. The dyes of the invention are soluble in commercially available membrane staining vehicles, are useful as probes for rapidly staining lipophilic structures such as membranes in cells or isolated from cells, and are well-retained therein. Methods of utilizing the dyes to detect stained cells both in vivo and in vitro are also disclosed.