The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Jun. 27, 2014
Applicants:
Inserm (Institut National DE LA Sante DE LA Recherche Medicale), Paris, FR;
Universite Pierre ET Marie Curie (Paris 6), Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Inventors:
Deniz Dalkara, Paris, FR;
Alvaro Rendon Fuentes, Paris, FR;
Jose Alain Sahel, Paris, FR;
Ophelie Vacca, Paris, FR;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/47 (2006.01); C12N 15/86 (2006.01); A61K 9/00 (2006.01); A61K 31/713 (2006.01); A61K 38/46 (2006.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 9/0048 (2013.01); A61K 31/713 (2013.01); A61K 38/465 (2013.01); C07K 14/4703 (2013.01); C12N 7/00 (2013.01); C12N 15/113 (2013.01); C12N 15/86 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01); C12N 2750/14142 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01); C12Y 301/00 (2013.01);
Abstract
Provided herein are methods for expressing a polynucleotide of interest in the retina of a subject. In particular, a method for expressing a polynucleotide of interest in the retina of a subject comprising the step consisting of injecting into the vitreous an amount of a vector containing the polynucleotide of interest in combination with an amount of an inhibitor of Dp71 expression is provided.