The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

Mar. 16, 2012
Applicants:

Catherine E. Safran, Bear, DE (US);

Mary C. Farach-carson, Houston, TX (US);

Xinqiao Jia, Newark, DE (US);

Padma P. Srinivasan, Newark, DE (US);

Amit Jha, Oakland, CA (US);

Inventors:

Catherine E. Safran, Bear, DE (US);

Mary C. Farach-Carson, Houston, TX (US);

Xinqiao Jia, Newark, DE (US);

Padma P. Srinivasan, Newark, DE (US);

Amit Jha, Oakland, CA (US);

Assignee:

University of Delaware, Newark, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 47/48 (2006.01); A61K 9/14 (2006.01); A61P 19/02 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 38/19 (2006.01); A61L 27/26 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48784 (2013.01); A61K 9/0019 (2013.01); A61K 38/18 (2013.01); A61K 38/1875 (2013.01); A61K 38/19 (2013.01); A61K 45/06 (2013.01); A61K 47/48246 (2013.01); A61L 27/26 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/414 (2013.01); A61L 2400/06 (2013.01); A61L 2430/06 (2013.01);
Abstract

A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.


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