The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Jan. 31, 2013
Applicant:
Original Biomedicals Co., Ltd, Tainan, TW;
Inventors:
Chia-Hung Chen, New Taipei, TW;
Chau-Hui Wang, New Taipei, TW;
John-Son Lin, Taipei, TW;
Tieh-Hsiung Chiu, Los Angeles, CA (US);
Jing-Yi Chen, Taipei, TW;
Pi-Hung Liao, Kaohsiung, TW;
Chia-Chi Su, Taichung, TW;
Wei-Chuan Liao, Kaohsiung, TW;
Assignee:
ORIGINAL BIOMEDICALS CO., LTD, Tainan, TW;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 47/48 (2006.01); A61K 38/14 (2006.01); A61K 31/164 (2006.01); A61K 31/198 (2006.01); A61K 31/496 (2006.01); A61K 31/661 (2006.01); A61K 31/704 (2006.01); A61K 47/02 (2006.01); A61K 9/107 (2006.01); A61K 9/51 (2006.01); A61K 47/18 (2006.01); A61K 47/22 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); A61K 9/1075 (2013.01); A61K 9/5115 (2013.01); A61K 31/164 (2013.01); A61K 31/198 (2013.01); A61K 31/496 (2013.01); A61K 31/661 (2013.01); A61K 31/704 (2013.01); A61K 38/14 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 9/5153 (2013.01); A61K 47/22 (2013.01);
Abstract
This invention provides the controlled-release method for a pharmaceutical composition comprising of metals in the drug carrier. The specific chelator is used to trigger the release of active pharmaceutical ingredients from chelating complex micelles. The drug release rate and half-life can also be controlled by manipulating the dosing sequence and the concentration of metal and specific chelator.