The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Sep. 25, 2015
Applicant:
National Center for Geriatrics and Gerontology, Obu-shi, Aichi, JP;
Inventors:
Misako Nakashima, Obu, JP;
Hiroshi Nakamura, Nagoya, JP;
Assignee:
NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY, Obu-Shi, Aichi, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/44 (2015.01); A61K 35/32 (2015.01); A61K 38/48 (2006.01); G01N 33/50 (2006.01); A61K 6/00 (2006.01); A61K 6/02 (2006.01); A61K 35/36 (2015.01);
U.S. Cl.
CPC ...
A61K 35/32 (2013.01); A61K 6/0017 (2013.01); A61K 6/0067 (2013.01); A61K 6/02 (2013.01); A61K 35/36 (2013.01); A61K 35/44 (2013.01); A61K 38/4886 (2013.01); G01N 33/5023 (2013.01); G01N 33/5064 (2013.01); G01N 33/5073 (2013.01); G01N 2333/96494 (2013.01); G01N 2800/18 (2013.01);
Abstract
A method of treatment for pulpitis and/or enhancement for dentinogenesis, includes using dental materials that include at least one of a protein having matrix metalloprotease 3 activities or matrix metalloprotease 3 precursor protein as an active ingredient. The dental materials can also contain a carrier having biocompatibility, and can contain at least one cell type among pulp cells, pulp stem cells, pulp progenitor cells, odontoblasts or cells that can differentiate into odontoblasts.