The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2017

Filed:

May. 31, 2006
Applicants:

Josee Roy, Germantown, TN (US);

Jeffrey C. Marx, Germantown, TN (US);

Inventors:

Josee Roy, Germantown, TN (US);

Jeffrey C. Marx, Germantown, TN (US);

Assignee:

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/075 (2006.01); A61K 31/765 (2006.01); A61K 9/00 (2006.01); A61K 31/00 (2006.01); A61K 47/10 (2017.01); A61L 31/06 (2006.01); A61L 31/16 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/765 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 31/00 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61L 31/06 (2013.01); A61L 31/16 (2013.01); A61L 2300/402 (2013.01); A61L 2400/06 (2013.01);
Abstract

In the present invention, Applicants demonstrate the effect of a biomembrane sealing agent on the development of chronic pain following tissue injury as well as acute pain in a model of acute inflammation. Applicants demonstrate the ability of this class of agents referred to as 'biomembrane sealing agents' to reduce the severity of hyperalgesia and allodynia following mechanical insult to the nervous system as well as their ability to reduce acute pain in a model of acute inflammation. Applicant describes the use of injectable or depot formulations of biomembrane sealing agent(s) for prophylactic treatment such as they could be administered after the insult (i.e. post-injury or post-surgery) but before the onset of acute or chronic pain. Alternatively, biomembrane sealing agents could be used to reduce the severity of acute or chronic pain after onset.


Find Patent Forward Citations

Loading…