The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2017
Filed:
Oct. 26, 2015
Applicant:
Pledpharma Ab, Stockholm, SE;
Inventors:
Jan-Olof Karlsson, Trondheim, NO;
Karl Reineke, Niskayuna, NY (US);
Tino Kurz, Linköping, SE;
Rolf Andersson, Vikingstad, SE;
Michael Hall, Albany, NY (US);
Christina McLaughlin, Albany, NY (US);
Sven Jacobsson, Stockholm, SE;
Jacques Näsström, Bromma, SE;
Assignee:
PLEDPHARMA AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); C07F 19/00 (2006.01); C07F 13/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/555 (2013.01); C07F 13/005 (2013.01); C07F 19/00 (2013.01);
Abstract
Methods for treatment of a pathological condition caused by oxidative stress in a patient comprise administering to the patient a mixed metal complex of a compound of Formula I, or a salt thereof, in an amount effective to reduce the oxidative stress. The mixed metals comprise calcium and manganese in a molar ratio of calcium to manganese in the range of 1-10: wherein X, R, R, R, and Rare as defined herein.