The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Mar. 25, 2015
Li-cor, Inc., Lincoln, NE (US);
Michael D. Furtaw, Lincoln, NE (US);
Jon P. Anderson, Lincoln, NE (US);
Mary J. Wirth, West Lafayette, IN (US);
Robert E. Birdsall, West Lafayette, IN (US);
Yimin Hua, Arlington, MA (US);
Zhaorui Zhang, Richland, WA (US);
LI-COR, INC., Lincoln, NE (US);
Purdue Research Foundation, West Lafayette, IN (US);
Abstract
A self-assembled engineered lattice of nanometer-scale silica particles, or other suitable particles generally resembling regularly-sized spheres, is configured in a separation bed for electrophoresis, isoelectric focusing, chromatography, or other voltage-induced separation of analytes. After separation, the analytes are immobilized on the separation bed and then ionized using matrix-assisted laser desorption/ionization (MALDI) for use with a mass spectrometer. The nanoparticles can be coated with polymers that activate to immobilize the analytes or assist with MALDI. The separation can occur in two dimensions.