The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Feb. 04, 2013
Applicant:

Ortho-clinical Diagnostics, Inc., Raritan, NJ (US);

Inventor:

Theodore J. DiMagno, Penfield, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 35/0092 (2013.01); G01N 35/00693 (2013.01); Y10T 436/115831 (2015.01);
Abstract

Disclosed is a use of reaction kinetics to generate multiple dose-response curves from a single reaction, thus eliminating the need to run a second experiment with additional sample, reagents, and time to cover a broader measuring range than is available in a standard assay. Using a single protocol, the differences in the reaction kinetics for different sample concentrations yield different responses at different measurement times. Selection of the appropriate dose-response curve cross-section increases the measuring range and accuracy of the assay from a single reaction without substantially increasing imprecision. Several overlapping dose-response curves are pieced together to provide a standard curve to ensure continuity throughout the expanded measuring range.


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