The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Jun. 20, 2012
Applicants:

Edward Marshall Alderman, Framingham, MA (US);

Brett Peter Masters, Belmont, CA (US);

Michael Francis Miller, Hollis, NH (US);

William Matthew Dickerson, Dorchester, MA (US);

Inventors:

Edward Marshall Alderman, Framingham, MA (US);

Brett Peter Masters, Belmont, CA (US);

Michael Francis Miller, Hollis, NH (US);

William Matthew Dickerson, Dorchester, MA (US);

Assignee:

ProterixBio, Inc., Billerica, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 29/02 (2006.01); G01N 27/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54393 (2013.01); G01N 27/745 (2013.01); G01N 29/022 (2013.01); G01N 33/54333 (2013.01); G01N 33/54373 (2013.01); G01N 2446/20 (2013.01);
Abstract

In one non-limiting aspect, the invention provides a method for detecting the quality of a biological molecule comprising forming a first mixture of ingredients comprising: (i) a first binding agent that specifically binds to a tag, wherein the first binding agent is attached to a solid support; (ii) a decoy comprising a first portion comprising the tag attached to a second portion comprising an anchor; (iii) a sensor attached to a second binding agent that specifically binds to the anchor; and (iv) a sample suspected of containing a high quality biological molecule comprising a tag, wherein the tag of the high quality biological molecule is accessible; allowing interaction of the ingredients such that the sensor provides an output signal.


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