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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9593340 B1

PDFFull Text
Date of Patent:
Mar. 14, 2017

Filed:

Oct. 02, 2008

Expression system for modulating an immune response

Applicants:

Ian Hector Frazer, St. Lucia, AU;

Julie Louise Dutton, Yeronga, AU;

Inventors:

Ian Hector Frazer, St. Lucia, AU;

Julie Louise Dutton, Yeronga, AU;

Assignee:

Admedus Vaccines Pty Ltd., Woolloongabba, AU;

Attorney:

Cooley LLP

Primary Examiner:

Reza Ghafoorian

Int. Cl.
CPC ...
C12N 15/79 (2006.01); A61K 39/145 (2006.01); A61K 39/245 (2006.01); A61K 39/29 (2006.01); C07K 14/005 (2006.01); C12N 15/67 (2006.01); C40B 40/08 (2006.01); C40B 50/04 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/79 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/245 (2013.01); A61K 39/29 (2013.01); C07K 14/005 (2013.01); C12N 15/67 (2013.01); C40B 40/08 (2013.01); C40B 50/04 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); C12N 2710/16222 (2013.01); C12N 2710/16234 (2013.01); C12N 2710/16622 (2013.01); C12N 2710/16634 (2013.01); C12N 2710/20022 (2013.01); C12N 2710/20034 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2770/24222 (2013.01); C12N 2770/24234 (2013.01);
Abstract

The present invention discloses methods and compositions for modulating the quality of an immune response to a target antigen in a mammal, which response results from the expression of a polynucleotide that encodes at least a portion of the target antigen, wherein the quality is modulated by replacing at least one codon of the polynucleotide with a synonymous codon that has a higher or lower preference of usage by the mammal to confer the immune response than the codon it replaces.

Find Patent Forward Citations

Frazer, Ian. (2017). Expression system for modulating an immune response (U.S. Patent No. 9593340). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9593340

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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