The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Mar. 14, 2014
Bayer Healthcare Llc, Whippany, NJ (US);
Ye Jin, San Ramon, CA (US);
John E. Murphy, Berkeley, CA (US);
Terry Hermiston, Corte Madera, CA (US);
Timothy Myles, Sunnyvale, CA (US);
Frank Dittmer, Duesseldorf, DE;
Michael Strerath, Duesseldorf, DE;
Uwe Gritzan, Cologne, DE;
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Abstract
This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin β complexed with heparin and/or heparin-like structure (ATβH). These ATβH binding proteins can block the anti-coagulant activity of ATβ to induce coagulation. Therapeutic uses of these antibodies and binders are described herein as are methods of panning and screening specific antibodies.