The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Jul. 16, 2013
The Scripps Research Institute, La Jolla, CA (US);
Rajesh Grover, Del Mar, CA (US);
Richard Lerner, La Jolla, CA (US);
Ian Wilson, La Jolla, CA (US);
Xueyong Zhu, San Diego, CA (US);
Rajesh Grover, Del Mar, CA (US);
Richard Lerner, La Jolla, CA (US);
Ian Wilson, La Jolla, CA (US);
Xueyong Zhu, San Diego, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
Provided herein methods of alleviating the symptoms of multiple myeloma in a patient or subject in need thereof, methods of treating multiple myeloma in a patient or subject, and methods of preventing development of multiple myeloma in a patient at risk thereof, such as a patient with monoclonal gammopathy of undetermined significance (MGUS), which methods include administering an agent effective to treat ainfection. The invention also relates to a new class of antigen, MG281 protein {also referenced as Protein M), that binds to various immunoglobulins with high affinity, and their uses in purifying immunoglobulins. The invention additionally relates to using MG281 protein and analog or derivative molecules for treating autoimmune diseases. Further provided are antigens and antibodies for use in the disclosed methods, and the identification of molecules that bind to MG281 protein.